<H1>Sulbutiamine -- Relentless Improvement LLC Shopping Cart</H1> <I>Limited Time Sale Pricing. A documented pharmaceutical grade Sulbutiamine, cost-effective 120 capsule size.</I> <P> <IMG SRC="https://store.nexternal.com/relentless/images/sulbutiamine7.jpg" ALIGN=right ALT="Sulbutiamine" NAME="Sulbutiamine" BORDER=0 HSPACE=10> <p>Be a careful shopper, this is a cost-effective <em><strong>120 capsule</strong></em> size.</p> <p>A documented pharmaceutical grade sulbutiamine.</p> <p>The effect of sulbutiamine can be described as a boost in mood, almost euphoric in some cases, comparable to a very strong coffee without the agitation and anxiety sometimes associated with caffeine. The duration tends to last the day, as opposed to caffeine which provides a short boost followed by let-down. <p>As a form of B-vitamin (thiamine), it is water soluble and excess is eliminated in the urine. <p>Popular with athletes and those involved with physical competition. <p> Sulbutiamine is rapidly absorbed and the blood concentration is maximum in 1-2 hrs after oral administration. The molecule is rapidly distributed in the whole body and is eliminated with a biological half-life of 5 hrs. <p> New research showing support for erectile dysfunction (1) <p>Bottled in FDA licensed, cGMP certified facility.<p> <p>100% purity, free of microbial and heavy metal contamination as documented by independent 3rd party lab analysis.<p> <a href="http://www.relentlessimprovement.com/learn/certificates_of_analysis" target="_blank">View Certificates of Analysis</a><p> Supplement Facts: <br> Expiration: Feb 2010<br> 120 capsules, 200 mg.<p> Serving Size: 1 capsule.<br> Servings per container: 120<br> Sulbutiamine 200 mg *<br> *daily value not established <p> Other ingredients: maltodextrin, gelatin (capsule). Store tightly in a cool dry area. Keep out of reach of children. Do not use if safety seal is broken or damaged. <p> Suggesed dose: Take 1-3 capsules per day, with breakfast or an AM meal. Do not exceed 3 capsules in a single dose as this may cause severe headaches. <p> Excessive doses may cause agitation or tremors. <p> Pregnant or breast feeding women should not use this product.<p> <p> Sulbutiamine crosses the blood brain barrier more easily than vitamin B1 because of its lipophilic properties. It leads to an increased formation of thiamine triphosphate (TTP) that acts as a regulator of the synaptic transmission of many neurotransmission systems.<p> Sulbutiamine is a thiamine derivative which has two different properties in comparison with vitamin B1 as a result of structural modification of free thiamine, namely opening of the thiazole ring, esterification of the alcohol groups and dimerization, with formation of a disulfide bridge.<p> (1) Urologiia. 2005 Jan-Feb;(1):32-5.<br> [Clinical efficacy of the drug enerion (sulbutiamine) in the treatment of patients with psychogenic (functional) erectile dysfunction] <br> Dmitriev DG, Gamidov SI, Permiakova OV. <p> Twenty patients with psychogenic erectile dysfunction received the drug enerion (sulbutiamine). After a 30-day course of enerion erectile function improved in 16 of the above patients. <p>A mean value of the international index of erectile function (IIEF) increased in them from 17.5 to 24.8 points. Improvement of cavernous arterial blood flow after the treatment was seen in 3 of 6 patients with arterial disorders. As shown by electromyographic examinations, cavernous electric activity normalized in 8 patients. 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